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Regulatory pathways for biomarker approval should be clarified to facilitate clinical implementation of validated markers (May et al., 2010)

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In this way, GSTP1 genotype could be considered a prognostic marker, able to reduce or avoid the peripheral neuropathy [36]

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A specialized single-photon emission computerized tomography (SPECT) scan called a dopamine transporter scan (DaTscan) is an alternative imaging exam, but it is expensive and not performed routinely